Endocrine Abstracts

Introduction: 11-Hydroxylase deficiency is a rare form of congenital adrenal hyperplasia characterized by glucocorticoid deficiency, hypertension, hypokalemia and virilization in females. We report a case of congenital adrenal hyperplasia due to 11beta-hydroxylase deficiency revealed by bilateral papilledema in the context of arterial hypertension.Case report: A 13-year-old patient, with no medical history, presented with complains of headache, vomiting ...

Introduction: Choroidal metastases are among the most common malignant ocular tumors. In the majority of cases, their origin is pulmonary in men and mammary in women. We present a rare case of choroidal metastasis from a vesicular thyroid carcinoma.Case presentation: A 35-year-old woman presented to our department complaining of progressive vision reduction in the right eye. Six years previously, she was operated for vesicular carcinoma of the thyroid wi...

Introduction: Graves’ ophthalmopathy, also called Graves’ orbitopathy, is a potentially sight-threatening ocular disease that has puzzled physicians and scientists for nearly two centuries. Generally occurring in patients with hyperthyroidism or a history of hyperthyroidism due to Graves’ disease, Graves’ ophthalmopathy is also known as thyroid-associated ophthalmopathy or thyroid eye disease, because it sometimes occurs in patients with euthyroid or hypoth...

Introduction: Graves’ disease is a common autoimmune disease that can be complicated by orbital damage sometimes threatening the visual prognosis. We report the case of a patient with Graves’ orbitopathy and we discuss the difficulties of clinical evaluation and therapeutic management.Case report: A 68-year-old woman presented to our department complaining of eye protrusion and progressive vision reduction in both eyes. She has had a history of...

Introduction: Diabetic retinopathy (DR) is a common microvascular complication of diabetes mellitus, leading to visual impairment among individuals of working age. Optical coherence tomography angiography (OCTA) has been developed to visualize the retinal microvasculature and choriocapillaris based on the motion contrast of circulating blood cells.Purpose: To investigate the qualitative microvascular changes in retinal vascular plexuses and choriocapilla...

Introduction: Pediatric intracranial hypertension (PIH) refers to increased pressure within the skull in children. While it is less common than in adults, hormonal factors can play a role in certain cases. Changes in hormone levels during puberty, particularly in girls, may contribute to this condition. This form is sometimes referred to as Idiopathic Intracranial Hypertension of Adolescence. We report a case of bilateral papilledema revealing idiopathic intracranial hypertens...

Introduction: Pituitary adenomas are common, and their impact on visual function is often significant, given the intimate relationship between the anterior pituitary and the optic pathways. Ocular symptoms may be indicative. Compressive optic neuropathy and oculomotor paralysis present a diagnostic challenge. This report details four cases where ocular manifestations played an essential role in establishing the diagnosis of pituitary macroadenomas.Observ...

Introduction: We report a case of pupil sparing third nerve palsy caused by diabetes. Case Presentation: A 68-year-old woman consulted for acute left upper lid ptosis appeared since 2 days ago. The patient complained of blurred vision and periorbital pain. No history of head trauma or infection was reported. The patient has been diagnosed with type II diabetes mellitus and arterial hypertension since 15 years. Ophthalmological examination revealed comple...

Introduction: Graves’ orbitopathy is an inflammatory autoimmune disorder. It is the most common extrathyroidal manifestation of Graves’ disease and it is the leading cause of proptosis in adults. We report 3 cases of Graves’ orbitopathy in order to detail ocular manifestations and protocol management in this disease.Observation 1: A 63-year-old woman was referred for left conjunctival redness. The best-corrected visual acuity was 10/10 in ...

Introduction: Graves’ disease (GD) is an autoimmune disorder characterized by hyperthyroidism, and it often involves the development of Graves’ ophthalmopathy (GO). The latter occurs in a significant percentage (25-50%) of Graves’ disease cases. Active and severe ophthalmopathy can lead to a worsened prognosis and, in extreme cases, result in blindness. Reports about late ocular manifestation of GD have become scarce due to improved management.<p class="abst...